Front Page Forums Matrix Coating Coating techniques? Re: Coating techniques?

Markus Stoeckli

Yes, it works. We use it in our lab and it’s relatively robust and reproducible. In a typical coating we spray 8 ml of saturated CHCA solution in 50:50 ACN/0.1%TFA using a TLC sprayer. The authors state:[quote] The sample is allowed to dry for 1-2 min before the next coating cycle[/quote]
IMHO it is a requirement to never let the sample completely dry in between spray cycles ❗ .