Front Page Forums General MSiMass Initial MSiMass List Re:Initial MSiMass List

Liam McDonnell

New entry for the database
m/z 2778 (linear MALDI ToF) in human chondrosarcoma (bone tumor)
identified as a nontryptic, C- terminal fragment of the protein vimentin, LIKTVETRDGQVINETSQHHDDLE using ETD on an Orbitrap Velos.
DOI of paper: DOI: 10.1021/pr301190g
Uniprot ID: P08670
On-tissue validation method: synthesis of isotopically labeled variant and comparison of on-tissue MS/MS

The same paper also reports another 350 top down ID’s but these have not been confirmed in the MALDI data.