Smoothing the MS Peaks

[Saira]

I am a new learner in the field, and wish to know that should we apply smoothing to the peaks, while doing kinetic studies of a particular protein, in which case areas of the peaks are very much important, and as you know that smoothing has no limit, and hence it changes the values constantly. What to do then?

[Markus Stoeckli]

MS images are typically generated from peak areas and smoothing will not enhance the result if you have many data points over the peak.

[Saira]

Dear Sir,

Thanks a lot for your extremely valuable piece of information. I would be extremely grateful to you if you could provide, if available, some reference which we may use for justification of the statement.

I wonder if I can get your contact information, if you feel appropriate.

With best regards!

Saira

[Markus Stoeckli]

This statement is based on my experience and can be challenged. Please use this forum to discuss MSI related aspects instead of PM.

[Saira]

Dear Sir,

I am extremely grateful for your kind response.

With best regards,
Saira

[Author]

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