Kamila Chughtai and Ron M. A. Heeren
Chem. Rev. 2010, 110 (5), 3237–3277

mass spectrometer is described as the smallest weighing scale ever used in the world. Mass spectrometry (MS) is a unique technique that has an interdisciplinary nature, which freely crosses the borders of physics, chemistry, and biology. Mass spectrometry is a great scientific tool due to its capabilities to determine the mass of large biomolecular complexes, individual biomolecules, small organic molecules, and single atoms and their isotopes. Right from the time of its invention in the first decade of the 20th century, mass spectrometry has undergone tremendous improvements in terms of its sensitivity, resolution, and mass range. It currently finds applications in all scientific disciplines, such as chemistry, physics, biology, pharmacology, medicine, biochemistry, and bioagro-based industry.




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